Antibodies to acetylcholine receptors Myasthenia Gravis
Blood tests Antibodies to acetylcholine receptors (serum) or antibodies to acetylcholine receptors.
Diagnostics for suspected myasthenia gravis (MG).
What is the muscle disease myasthenia gravis (MG)?
- AChR MG can occur at any age, in both men and women
- Relatively more women than men suffer from the disease
- MG is not hereditary
- The symptoms of MG can vary greatly from person to person
- The severity of MG can vary greatly even in one person
Myasthenia gravis (MG) is the name of a condition that leads to the non-functioning or inadequate functioning of muscles. This text is about myasthenia gravis with antibodies to acetylcholine receptors (AChR MG).
There are more myasthenias that, like AChR MG, are relatively rare, for example, Lambert-Eaton myasthenic syndrome (LEMS).
In MG, signals from the nerve are not properly transmitted to the muscle. Normally, this is done by a chemical (acetylcholine) produced at the tip of the nerve and taken up by specially sensitive receptors in the muscle. In MG, many of these receptors are blocked or broken.
The nature and severity of the symptoms of MG vary from person to person.
Some common symptoms include:
- drooping eyelids and double vision
- little mimicry
- difficulty chewing and/or swallowing
Method used: RIA
Explanation of result autoantibodies against acetylcholine receptorsThe
result is good if the antibody ratio is below 10.
Regardless of the result, antibodies againstM3 muscarinic
acetylcholine receptors cannot
be
used
to exclude oranticipate
a Mysthenia. WhenMyasthenia
gravis
is suspected
, antibodies to nicotinic muscular acetylcholine receptors
(ACHR) or to muscle specificreceptor tyrosinkinase
(MuSK)
should
be examined.
But we do not offer these tests, for this you should see your specialist.
Antibodies to M3-muscarinic acetylcholine receptors can also
be found
in SjögrenSyndrome
or in healthy people, among others. The diagnostic value is therefore quite low.
This test has limited diagnostic value and should be considered in conjunction with ACHR and MuSK. The advice is to have this test performed only by the hospital and not to order it from Blood Values Test. The interpretation of the result should be done by your own specialist.
