Glyphosate: microbiome damage from pesticides
NEW Glyphosate from urine: measure the damage of pesticides on your microbiome.
(Code: GLYPHU) from morning urine
Glyphosate is the most widely used herbicide worldwide. It is mainly used to control weeds in farmland.
A urine test for glyphosate can detect the presence and concentration of glyphosate and its metabolites in the body, which may indicate exposure to this drug. This test is used to assess exposure to glyphosate, which may be relevant for health studies or monitoring exposure to agricultural chemicals.
By using glyphosate, the so-called Shikimate metabolic pathway of the plant is inhibited, resulting in the inability to form essential amino acids.
Shikamate pathway is a seven-step metabolic pathway used by plants, among others.
The mechanism of action of Glyphosate in plants is the disruption of the shikimate pathway, which is involved in the synthesis of the essential aromatic amino acids, phenylalanine, tyrosine and tryptophan.
Until recently, it was stated that Glyphosate is not harmful to humans or mammals because the shikimate pathway is absent from all animals and humans.
However, gut bacteria do have a shikamate pathway
Thus, due to the large amounts of Glyphosate used in agriculture, the gut bacteria are greatly harmed, which can greatly harm the microbiome.
Glyphosate was discovered by Monsanto chemist John E. Franz in 1970 and marketed in 1974 under the trade name Roundup. Although glyphosate and products such as Roundup have been approved by regulatory agencies worldwide, concerns about its effects on humans and the environment have remained. A 2016 report by the WHO-FAO Joint Commission on Pesticide Residues stated that the use of glyphosate formulations does not necessarily pose a health risk, with an acceptable daily intake limit of 1 milligram per kilogram of body weight per day for chronic toxicity.
Glyphosate may be potentially dangerous to humans because of concerns about possible health effects, including a link to certain cancers, as indicated by some studies and organizations. However, there is still considerable debate and research going on about the extent and nature of these risks.
