Hepatitis Bc-al. (anti-HBc)
Interpretation of a "core-only" is difficult. True Hepatitis diagnosis requires multiple tests. Interpretation remains difficult and it is often not clear whether the person in question is immune (has experienced infection). The detection of anti-HBc (IgG / IgM) indicates contact with hepatitis B viruses. For further differentiation, at least anti-HBc IgM and HBs antigen should be determined. A single positive anti-HBc result is not specific enough.
Sometimes this test is requested for example by a doctor performing fertility treatment.
Antibodies (IgM AND IgG) to HBcAg; indicates old or recent infection; not present
after vaccination; good screening marker for "ever HBV infection passed
". Isolated, positive anti-HBc usually means a recovered
infection or a false positive result. Very rarely, an
isolated anti-HBc is infected, sometimes even chronically with undetectable
HBsAg.