iGene DNA test Farmaco (including MTHFR)
iGene DNA Test: Pharma
Drug sensitivity & pharmacogenetics, personal characteristics,
Through a saliva sample we map out part of your DNA. This gives you information about your genetic predisposition, broken down into different health topics:
- Sensitivity to commonly used medications and pharmaco-profile-
Personal characteristics
How does it work?
You will receive an iGene DNA kit at home with which you will take a DNA sample. You send this back with the provided return envelope. Your DNA is then analyzed in a medical laboratory and after 4 to 6 weeks the iGene Gene Passport is ready. You can access the results using the iGene app or download as a pdf report.
One-time test, lasting value
Your DNA is unique and remains unchanged throughout your life. A DNA test is therefore not a snapshot, but a valuable investment that provides information from which you can benefit throughout your life.
Drug Sensitivity & Pharmacogenetics (including MTHFR)
DNA variations affect the activity of enzymes and transport proteins, resulting in many individual differences in the speed at which drugs are processed in the body. As a result, certain drugs may affect some people better than others, or you may suffer more side effects than someone else.
The DNA test preventively identifies the medications to which you may react abnormally. This allows a doctor or pharmacist to immediately choose the right medicine and dosage for you.
Pharmaco-profile
The pharmacogenetic report is an overview of your personal enzyme activity which you can easily share with your doctor or pharmacist. The following enzymes are mapped:
BChE enzyme, CYP1A2 enzyme, CYP2B6 enzyme, CYP2C19 enzyme, CYP2C9 enzyme, CYP2D6 enzyme, CYP3A4 enzyme, CYP3A5 enzyme, DPD enzyme, Factor V Leiden, F2, SERPINC1, PROC, PROS1, HLA-A*3101 / HLA-B*1502, HLA-B*5701, IL28B, MTHFR enzyme, NUDT15 enzyme, SLCO1B1 transporter protein, TPMT enzyme, UGT1A1 enzyme, VKORC1 enzyme.
Drug sensitivity
Any abnormalities in enzyme activity may affect how medications work. Drugs included in the iGene Passport include:
abacavir, acenocoumarol, amitriptyline, aripiprazole, atomoxetine, atorvastatin, azathioprine, brexpiprazole, capecitabine, carbamazepine (asians and eur), celecoxib, citalopram, clomipramine, clopidogrel codeine, doxepin, efavirenz, eliglustat, escitalopram, fenprocoumon, phenytoin, flecainide, flucloxacillin, fluorouracil, flurbiprofen, haloperidol, ibuprofen, imipramine, irinotecan, lansoprazole, lornoxicam meloxicam, mercaptopurine, methotrexate, metoprolol, mivacurium, nortriptyline, estrogen-containing contraceptives, omeprazole, oxcarbazepine, pantoprazole, paroxetine, peg-interferon and ribavirin, pimozide piroxicam, propafenone, risperidone, sertraline, simvastatin, siponimod, succinylcholine, tacrolimus, tamoxifen, tegafur, tenoxicam, tioguanine, tramadol, venlafaxine, voriconazole, warfarin, zuclopentixol.
Personal Characteristics
This section provides information in the "fun or useful to know" category. The following topics are covered:
- Alcohol hypersensitivity
- Androgenetic alopecia (hair loss)
- Bitter taste perception
- Caffeine Sensitivity
- Hereditary fructose intolerance (HFI)
- Gluten intolerance (celiac disease)
- Norovirus resistance
- Lactose Intolerance
- Chance of red hair
- Fast twitch muscle fibers
- Susceptibility to SARS (2003)
- Sensitivity to pain and stress (COMT gene)
- Hemochromatosis (iron accumulation)
- Thrombophilia
Regular new updates
iGeneregularly adds new information to the Gene Passport. Also already completed profiles then receive an update with new characteristics or other relevant information based on your DNA profile.
Personalized counseling
After taking the DNA test, would you like someone to personally explain the results of your test? Or do you need guidance in adapting your lifestyle? We are happy to put you in touch with an iGene Certified Professional, who knows all about DNA results, to discuss your results and help you further.
However, most people buy the iGene Health test, which is exactly the same as this pharmaco-test, with the extra feature that it also includes the risks of contracting diseases, for just a few extra bucks.
For more information see the brochure here "iGene Passport something for me"?
Or watch this excerpt from the programTegenlicht
