LGI1 antibodies
LGI1 antibodies are autoimmune antibodies directed against the LGI1 protein, which stands for Leucine-Rich Glioma Inactivated 1. This protein plays a crucial role in the regulation of synaptic activity and neural communication, especially in the brain.
The presence of LGI1 antibodies in the blood is characteristic of a specific type of autoimmune encephalitis, known as limbic encephalitis. This is an inflammatory disorder of the limbic system, a part of the brain responsible for emotions, memory and the autonomic nervous system.