Melatonin from serum at lab

Melatonin from Serum (MELAT)

Due to the complex pre-analysis, this test can only be taken at the lab in Mönchengladbach.

There is a pronounced circadian rhythm with maximum values at night. A circadian rhythm is a natural, internal process that regulates sleep-wake rhythms and repeats about every 24 hours. These rhythms are influenced by external cues such as light and temperature, but are primarily regulated internally. A "pronounced" circadian rhythm means that this rhythm is very distinct and regular, with a strong distinction between active and rest periods.

Therefore, in serial determinations, samples should always be taken at the same time.

reference values:
<30 pg/ml during the day
at night 30 - 150 pg/ml

Measurement method: liquid chromatography-mass spectrometry (LCMS)

Clinical Indication: Clarification of disturbed sleep-wake rhythms

Assessment Decreased or increased: sleep disorders or disturbed sleep-wake rhythm. Increased: impaired liver function, during long periods of darkness, diet rich in tryptophan, high doses of vitamin B6, therapy with MAO inhibitors. Deteriorated: blindness, chronic stress, shift work, jet lag, hyperthyroidism, vitamin B6 deficiency

Melatonin is one of the most important biomarkers of health, especially with respect to the biological clock

Melatonin is a hormone produced by the pineal gland (a small gland in the brain) that helps the body sleep and wake up. It is often used as a supplement to treat sleep problems.

A salivary test for melatonin can be useful to determine whether a person has healthy melatonin production and to monitor the effectiveness of supplements. Measuring melatonin concentration in saliva can also help determine the timing of taking the supplement.

Melatonin is a hormone produced by the pineal gland in the brain that plays an important role in regulating the sleep-wake cycle.

A melatonin salivary test can be performed for several reasons, including:

• Sleep problems: If someone is having trouble sleeping, a melatonin test can help determine if there is an underlying problem with melatonin production.
• Jet lag: A melatonin test can also be used to measure melatonin production in people who suffer from jet lag.
• Circadian rhythm disorders: A melatonin test can be performed in people suffering from circadian rhythm disorder, in which the body does not respond appropriately to day and night cycles.
• Hormonal imbalance: Melatonin production can be affected by hormonal imbalance and a test can help determine this imbalance.